Description: Andrew Largeman (Braff) shuffled through life in a lithium-induced coma until his mother's death inspired a vacation from the pills to see what might happen. When he travels from L.A. back to his hometown, he meets Sam (Portman), a girl who is everything he isn't. Her warmth and fearlessness give him the courage to open his heart to the joy and pain of the infinite abyss that is life. (Fox Searchlight Pictures)