Mixed or average reviews - based on 28 Critics

Critic score distribution:
  1. Positive: 15 out of 28
  2. Negative: 4 out of 28
  1. Gets under your skin with laughs that are fast, slick and slippery and with visuals as vivid as anything this side of Demerol.
  2. Surprise of surprises, it's a blast.
  3. Oscillates between streaky black comedy and sanitary instruction.
  4. Reviewed by: Jan Stuart
    Warts and all, Osmosis Jones is the year's ultimate bodily functions comedy.
  5. A genuinely eccentric comedy that explodes with funny ideas and expresses most of them in wildly original animation.
  6. Resuscitates the filmgoing summer with a vital jolt of pure piss and vinegar.
  7. Reviewed by: Jay Carr
    In a dismal summer for movies, Osmosis Jones is a fresh breath of foul air.
  8. 75
    Likely to entertain kids, who seem to like jokes about anatomical plumbing. For adults, there is the exuberance of the animation and the energy of the whole movie, which is just plain clever.
  9. Should you take the kids? Boys 8 to 11 are the target audience for this gross-out film. A better question might be, should they take the parents?
  10. 70
    Often very smart about being silly.
  11. Reviewed by: Robert Koehler
    The most extensive interplay of live action and animation since "Who Framed Roger Rabbit?"
  12. Often wickedly funny, but about halfway through, the premise becomes -- shall we say? -- intestinally overextended.
  13. 63
    David Hyde Pierce is hilarious as Drix, a take-charge dose of medicine. No performer is better at wringing laughs from an unflappable --- make that semi-flappable - delivery.
  14. Reviewed by: Claudia Puig
    The animation sequences -- the movie's best moments -- hurtle by at breakneck speed, while the live-action portions are a bit sluggish.
  15. When we're outside Frank's body, Osmosis Jones drags. When we're inside him, it zooms.
  16. 60
    The flat, gross-out live-action bits, directed by (surprise!) Peter and Bobby Farrelly, don't jive with the zippy, Tex Avery-style animated segments, directed by former storyboard artists Piet Kroon and Tom Sito.
  17. 60
    Too crude for the kids and not crude enough for connoisseurs of the "Something About Mary" school of hair jism and balls caught in zippers, Osmosis Jones seems doomed to fall between the cracks.
  18. 50
    While there's no denying that the film's animation is technically impressive and is sometimes quite clever, its inventiveness is frequently at the service of gags so distasteful that gag is the operative word.
  19. That Osmosis Jones plays like a sloppy hodgepodge is no surprise: The live-action scenes were done by the Farrellys, the animation by Sito and Kroon (whose names sounds like bodily functions), and the script was penned by another first-timer, Marc Hyman. Nobody seems to be on the same page.
  20. Reviewed by: Bill Wyman
    Remains stubbornly one-dimensional. The gags are so resoundingly and innocently pre-adolescent that it's really hard to see how the film managed a PG rating.
  21. Reviewed by: Chris Hewitt
    Classy voice work (intriguingly, the hero, heroine and villain are all voiced by black actors -- Chris Rock, Brandy and Laurence Fishburne)
  22. Osmosis is really an occasion for the brothers to take their culture- debasing scatology to a PG crowd.
  23. Young viewers may guffaw, but seasoned fans of "There's Something About Mary" will be disappointed.
  24. The ideas are there, hints of genius, but no one ignites them. Add Osmosis Jones to that list of universal enigmas, and, more specifically, how the Farrelly Brothers could have done so little with so much.
  25. More than a bad movie, it's an anti-movie.
  26. It's no funnier than your average grade-school biology lesson and less pedagogically useful than your typical Farrelly brothers comedy.
  27. 30
    Cathartically disgusting adventure movie.
  28. 10
    Should never have been released, not even on video. It should have been placed in a hazardous waste container, encased in concrete and dumped into the Farrelly brothers' septic tank.
User Score

Generally favorable reviews- based on 35 Ratings

User score distribution:
  1. Positive: 8 out of 9
  2. Negative: 0 out of 9
  1. Jamalh.
    Sep 29, 2005
    To be seen by people who can distinguish the scientific truth for more clarification.
  2. Jan 31, 2013
    A messy but good movie in which appear many swearwords.
  3. Jan 4, 2013
    This has to be one of my favorite semi-animated films. It's not brilliant and I won't consider it a masterpiece, but I will say that IThis has to be one of my favorite semi-animated films. It's not brilliant and I won't consider it a masterpiece, but I will say that I thoroughly enjoyed every part of the movie that was animated. Bill Murray & Chris Elliott's performances are really sub par and very weak. Elena Franklin (the little girl) is perhaps the only "actor" that seems to be trying. Luckily the non-animated parts don't take up to much screen time. The voice actors on the other hand do a fantastic job and play their characters phenomenally. Rock, Hyde Piece, Fishburne & Shatner were perfectly cast. Just a shame that Fishburne's character isn't given a bit more attention as he is absolutely great as a villain. Overall: A great fun movie that could have been a larger success if the live action actors would have made the same effort as the animated voice actors. Full Review »