Following the Spider-Man (1981) cartoon, NBC decided they wanted Spidey to go in a different, more accessible direction. So in order to reach a wider audience, they added the X-Men character Ice-Man, a new character called Firestar, gave Peter Parker a room that turned into a secret superhero hi-tech headquarters, and renamed the show SPIDER-MAN AND HIS AMAZING FRIENDS. What kid can't relate, right? Regardless of the reasoning, the changes must have worked many people watched this show.
Not only do the Spider-Friends fight Spider-Man's enemies (Dr. Octopus, Scorpion, Green Goblin, Kraven the Hunter, Swarm (not Fritz Von Meyer in this reality, just a bunch of bees), The Chameleon, Electro, Mysterio, Kingpin, The Shocker, The Sandman, and The Beetle) and other Marvel universe villians (Dr. Doom, Magneto, Loki, Mordred, The Red Skull, and The Juggernaut), but also new villians made only for the show.
There were episodes when the Spider-Friends teamed up with other Marvel superheroes like Sunfire, Captain America, Shanna the She-Devil, Namor the Sub-Mariner, Dr. Strange, The Hulk, Thor, The Black Knight III, and the X-Men.
For the second season, the title became THE INCREDIBLE HULK AND THE AMAZING SPIDER-MAN, becoming an hour show that featured 30 minutes of Spidey (and friends) and 30 minutes of Hulk. By third season, the concept was the same, only in reverse order with a new title, "THE AMAZING SPIDER-MAN AND THE INCREDIBLE HULK". Despite the name changes, this area will focus on all three seasons of Spidey and friends.