Over the last century at least four thousand four hundred people who vanished without a trace off the face of the planet. Last night they were all returned to Detroit having not aged a day and with no memory of what happened to them.

LaDonna signs up for fifteen more minutes of fame but quickly realizes she doesn't have the clout she once had, meanwhile Shanice takes a step towards repairing her relationship with her daughter.

Finally there is some good news for a few of the 4400. Andre looks to study some of his new friends but mistakes from his past begin to affect him in present day. Rev finds some information about his son.

Jharrel and Keisha must earn the trust of the 4400 if they truly want to help keep them safe. Hayden convinces LaDonna and Andre to visit Ypsi Med and Rev continues to grow his flock.

Logan's adjustment to Shanice's return has been harder than he let on, meanwhile, Rev is beginning to see the light. Mildred lets her emotions get the better of her, possibly endangering the rest of the 4400.

Everyone is still reeling after Mildred's on camera performance. The government tries to figure out their next move. Rev is confused by his new ability, Jharrel get some unexpected news, and no one seems to know Ladonna's whereabouts.

With everyone at the Bois Blanc still on edge, the government deals another blow to the 4400. Meanwhile, Jharrel gets some shocking information about his brother, Shanice and Andre continue to grow closer, and Mildred resurfaces.

Shanice prepares the Bois Blanc for a celebration while others are preparing for war. LaDonna returns to the hotel. Hayden realizes the comfort of Kaminsky home may not be what is safest. Jharrell reunites with his brother.

Logan is the only witness to a savage crime. Claudette stands up to a group of anti-4400's. Mildred rallies the troops when she fears Milicent might be in trouble and we get a glimpse into the sisters' lives growing up.

Tensions rise as an attack is made on Bois Blanc. Shanice and Logan do their best to keep Hayden safe, while Claudette and Jharrell try to reason with Manny. Mildred still believes her sister can be saved, and LaDonna takes to the streets.