A charming thief arrives in San Francisco with murderous plans to steal a priceless jewel collection. Ironside's assignment: to make sure the jewelry is transported into and out of a museum without incident.

Ironside agrees to undergo exploratory surgery that could restore his ability to walk - or kill him. At that hospital, a masked assailant escapes with stolen drugs after murdering a security guard.

Just before his spinal surgery, Ironside asks the public to help find the person who stole drugs from the hospital and killed a guard. The chief does not know that the same man has been planning for Ironside to die on the operating table.

Mark's eyewitness account casts suspicion of murder on a veteran police detective. When his alibi is disproved by Ironside, the sergeant stops at nothing to find someone who will confess to the crime.

The police commissioner asks Ironside to prove that an angry young African-American activist did not stab a racist shopkeeper to death during a riot.

On vacation in the mountains, Ironside tries to find a former hunting buddy. The chief is then kidnapped by a wealthy rancher and his son, who have been plotting to steal the land belonging to Ironside's old friend.

A notorious TV muckraker, now running for public office, is receiving death threats. Ironside, who can't stand the man or his tactics, is forced to investigate.

A former detective, now living on the streets, alerts Ironside about the death of another homeless man. He joins Ironside on the case and discovers the death is connected to someone passing bogus checks.

Numerous bits of evidence indicate Ironside's former girlfriend shot and killed her husband, but the chief wants all of the facts before an arrest is made. Ironside also thinks the "victim" might still be alive.

Officer Whitfield is shot and critically wounded in a pawn-shop holdup. As Ironside works to solve the crime, he recalls how he first met Eve several years earlier while he was still walking and she was a rich society girl.

A millionaire is murdered, his chauffeur is severely beaten, and a smoke bomb is shot into Ironside's office - all in the presence of a talking mynah bird. Ironside and his team try to find out what the bird knows.

Ironside writes a letter of recommendation for a pool hustler who plans to attend college. When the young man changes his mind and agrees to a high-stakes game against a legendary billiards champion, the chief wants to know why.

A fierce but well-trained dog found at a murder scene did not belong to the victim. Ironside takes the German shepherd to his office; he wants to see if its owner can help identify the killer.

After spotting a previously undiscovered portrait for sale, Ironside scours Mexico to find its presumed-dead painter and clear him of a murder charge.

Eve's teenage niece faces reform school after her second arrest for possession of illegal drugs. As Ironside tries to find the source of supply, the girl escapes from Eve's home and disappears.

Ironside's Aunt Victoria suspects foul play when one of her card-playing friends vanishes. Despite her nephew's admonitions, Victoria and her bridge partners shadow their missing friend's husband, who insists his wife left him.

A friend of Mark is found drunk and bending over an assault victim. Even though his night-school law teacher and Ironside lend assistance, Mark becomes frustrated with the legal process as he tries to help his friend gain an acquittal.

A society widow makes ominous predictions about Ironside and his assistants. Her visions start coming true as the team tries to recover a two-million-dollar painting being held for ransom.

A one-time movie star is missing, and the people who know her can't say where she went. Ironside and his assistants encounter forgery, extortion, and attempted murder in their efforts to find the young actress.

Eve becomes romantically involved with a writer who seems to be living beyond his means. Ironside traces a theft ring to a telephone answering service used by Eve's boyfriend, who becomes the prime suspect in a series of home burglaries.

Stakeholders in a pharmaceutical company try to gain approval for a dangerous anti-rejection medicine just before a lucrative merger. Ironside thinks the owner knows who has been frightening her with accidents and strange voices.

Ed's friend, a major-league baseball player, receives a series of threatening letters. He then claims an object was thrown at him in the outfield during a game. Ironside must find the culprit before the attacks become more deadly.

A young woman is found dead from internal bleeding after an abortion. Using previous cases and clues provided by Ironside, Eve goes undercover to track down an abortionist who has had several other patients die.

Ironside and his team, along with a U.S. Army bomb-disposal unit, respond to threats on a college campus. Although the devices found are relatively harmless, the chief believes that might change.