Everything in Scott McCall's life is starting to fall into place. He gets a spot on the First Line of his Lacrosse team and a date with the woman of his dreams. But when he gets bitten by a wolf, the people around him could be in danger.

Scott and Stiles discover that the werewolf curse can also be triggered by anger, besides the full moon. With the lacrosse game coming up, Jackson and his girlfriend, Lydia, hope to humiliate Scott. Will Scott be able to control his rage?

Responding to Scott's howl, the alpha savages Derek and traps Scott and Stiles in their high school. Events escalate even further when Allison, Jackson, and Lydia are lured to the school as well with a phony text message.