After a deadly virus wipes out humanity, Phil Miller searches the country for more survivors.

Phil discovers he is NOT the last man on earth as he finds Carol, unfortunately they are opposites she is a nerdy clean freak, but beggars can't be choosers.

Phil finally agrees to marry Carol even though he thinks it's rather silly, given that they are the last two people on Earth. Adjusting to married life goes well, until he suddenly runs into the beautiful, and unattached, Melissa.

Phil must work fast in order to save human existence.

Phil's efforts to bed Melissa are stopped short by the second last man on earth.

After the confession at the bar with Melissa, Phil grows more annoyed with the presence of Todd. Carol pressures Phil to clean the toilet pool.

Phil gets a cow to prove to the group that he is worth something after Todd becomes the go-to man. Carol pressures Phil for her to move in with him.

Phil asks God for a do-over, and two women suddenly arrive. He plans to meet them for dinner, and goes back and lies to Carol that he wants to go camping alone.

Phil is outcast after everyone finds out about him telling the new women that his wife is dead.

Phil attempts to alter his "Alive in Tucson" signs so no more men will show up, but he ends up marooned on one of his billboards with no one to help.

The cul-de-sac has a re-election for President of the United States.

Tandy realizes that he is super-jealous of New Phil's relationship with Carol, so he decides he must win her back.