Karl pitches a bizarre idea for a film, in which the comatose hero, played by 'Clive Warren,' has his brain transplanted into hiswidow's head.

Karl imagines what life would be like if he had an exact doppelganger. Ricky poses a logic riddle that Karl has difficulty solving.

Ricky teaches Karl some interesting facts about animals. Karl offers a misguided theory about evolution then recounts the latestscientific breakthroughs in medicine.

Karl addresses one of his pet peeves, animals who are treated like people, and issues a public safety announcement for chameleons.He considers the question, 'Does the brain control you or do you control the brain?"

Karl shares that he often goes on walks to observe ants, moths and other insects and that he once saw a bee have a heart attack.Karl asks if everything were the same size as humans, what would be the best animal to be.

Karl discovers he has a kidney stone and spends time in the hospital. Ricky stops by to visit and mock him. Karl considers animalsthat look like things and wonders if that's difficult for them.

Karl says he wouldn't mind life as a littler person, since everything from food portions to cities would be bigger for him. Stephenrecounts his night out at a London club.

Ricky reads some predictions for the future from an academic study, which leads Karl to share his theories. Stephen asks the guys iftoday were the end of the world, what would they do with their last day?

Karl contemplates how many different species are actually needed in the world, and whether or not we should keep looking for new forms of life. Karl questions if inventions like modern vacuum cleaners and toasters are necessary.

Ricky, Stephen and Karl discuss the nature of art, and whether old urinals or sharks in formaldehyde should be considered artistic works.

Ricky and Stephen challenge Karl to describe his ideal version of the world as conjured in a magical isolation tank, but Karl is suspicious of a perfect life. Karl describes his theory of the "Problem Hole."