Description: When a writing assignment lands journalist Raoul Duke (Depp) and sidekick DR. Gonzo (Del Toro) in Las Vegas, they decide to make it the ultimate business trip. But before long, business is forgotten and trip has become the key word. Fueled by a suitcase full of mind-bending pharmaceuticals, Duke and Gonzo set off on a fast and furious ride through nonstop neon, surreal surroundings and a crew of the craziest characters ever. (Universal Pictures)