A group from Nonnatus House travels overseas in order to assist a struggling clinic in South Africa.

The Nonnatus House staff face great change, Phyllis and Barbara help a battered wife, while Sister Mary Cynthia becomes increasingly fragile.

An explosion at the docks badly affects the husband of a new mother, Patsy feels under pressure, and Sister Ursula continues to test the patience of everyone at Nonnatus House.

Sister Ursula continues to make life difficult for the staff of Nonnatus House, while sweeping reforms place the maternity unit under threat.

Nonnatus House advertises for a new midwife, while Trixie, Sister Winifred and Tom help an expectant mother in a difficult situation.

Nonnatus House welcomes a new recruit, Fred and Violet take in a vulnerable young man, Sister Monica Joan makes a discovery, and Trixie meets a charming dentist.

The effects of thalidomide continue to take their toll on a former patient, leaving Patrick guilt-ridden, while a shocking incident leaves Phyllis consumed with guilt of her own.

A new contraceptive clinic adjacent to the Nonnatus maternity unit causes trouble, while an unexpected letter to Barbara sends everyone into a frenzy.