The Vampire Diaries star Kat Graham takes a bite out of Shameik Moore. Can this Spider-Man fight back? Then it's a standup standoff when two comedy giants, Nikki Glaser and Brad Williams, start throwing punch lines.

One of basketball's hottest stars Lonzo Ball tries to dunk on the king of autotune T-Pain. Then friends become foes as a slimmed down Kevin Smith goes head-to-head with Jason Mewes. Jay and Silent Bob will never be the same!

R&B singer Ne-Yo battles Mike Colter to see if he's as tough as Luke Cage. Next it's a pop star party when Christina Milian and Ashlee Simpson see which voice can deal more pain all from Universal Orlando Resort in Orlando, Fla.

Straight Outta Compton's Jason Mitchell channels Eazy-E against American Horror Story's chilling Adina Porter. Then 90's TV teens are grown up as Married With Children's David Faustino and Blossom's Joey Lawrence duke it out with bars.