Watson considers making a major life change after reading her own therapy file while Holmes and she investigate the murder of her former psychologist.

Sherlock finds himself in possession of a severed head and a temporary case of amnesia. Watson helps Holmes retrace his footsteps to put the pieces together.

Holmes and Watson deal with nuclear security when a former Japanese crime syndicate member is found dead. Captain Gregson is shook when he hears a confession from a family member.

Sherlock faces serious problems hindering his recovery as he and Watson track down a serial killer hunting in Holmes' circle.

Holmes' former sobriety sponsor asks for help with an illegal endeavor in order to save his brother. Holmes and Watson investigate the poisoning of a biology professor who was working on a secret project.

Sherlock and his father attempt to repair their strained relationship upon learning of a death within their family. Holmes and Watson discover a link between their latest case and the world of Egyptian antiquities.

Holmes engages an old foe to protect his father, Morland. Holmes and Watson search for a killer connected to the tobacco industry when a lawyer, who was reviewing a major cigarette distributor's finances, is murdered.

Detective Bell considers leaving the NYPD after he is recommended for a once-in-a-lifetime career opportunity; Holmes and Watson investigate the disappearance of a young woman who led a double life as a financial dominatrix.

Holmes and Watson investigate the death of a relocation expert who was hiding a secret career. Watson suffers a setback in her attempts to adopt a child.

It's a race against time for Holmes and Watson when Bell becomes a victim of a bioterrorism attack at the precinct. During the quarantine, Gregson and Bell suspect they are trapped inside with the terrorist.

Holmes and Watson discover that the murder of a robotics engineer may be connected to his secret research in the area of real-life teleportation.

The duo suspects a murdered zoologist was killed because of his numerous affairs or his trailblazing research; Holmes finds himself the victim of identity theft after his medical records are stolen.

Holmes and Watson are brought a case of a deceased man who wrote predictive obituaries, including Sherlock's, which are beginning to come true.

Holmes and Watson race to locate a missing woman; Holmes' friend becomes the prime suspect in the woman's disappearance.

A new victim appears and the game is on between Sherlock and Michael. But not all is as it seems.

Holmes works to find Rowan's murderer before Watson is charged with the crime.