Investigators examine evidence left at an automobile accident to determine if this was murder, including footprints leading away from the scene, blood on the outside of the car, and the victim was not wearing shoes in the middle of winter.

After a corpse is found without its head and hands at a compose site, a single finger tip leads to the identity of the body. A single dog hair found on the body, witness tips, and blood evidence lead to the suspect.

The bodies of a murdered Florida couple are discovered along a dirt road. A man with a criminal record is suspected since his driver's license is discovered at the crime scene, until DNA extracted from a spoon points to another man.

After moving with her family from Sudan to the United States, a little girl becomes ill and dies; authorities must determine how and why it happened.

Karen Slover, 23, model and mother, is killed in 1996. Thanks to a forensic geologist, the police may now be able to solve the puzzling IL case after many years.

The world of high rollers and offshore gambling becomes the focus of the investigation into a Wisconsin triple murder.

A funeral handyman is found dead underneath a parked car in Paterson, New Jersey. Although a medical examiner rules the death an accident, three years of investigation and a second autopsy prove it was murder.

A local celebrity is killed and a passenger injured in a hit-and-run boating accident in New York State, leaving very little forensic evidence.

Bible missionary student is murdered whilst baking cookies on Mother's Day Weekend for her mother. Police use a bloody palm print to provide forensic evidence as to the identity of her rapist and murderer.

A twelve-year-old girl claims that she was abducted and sexually assaulted. However, her story seems unbelievable until police discover fibers on her clothing.

A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

For ten years, the disappearance of a college co-ed remained a mystery. And then new scientific testing cast a different light on a man who had been a suspect all along. Originally aired as Season 11, Episode 26.

The murder of 53-year-old Paul Gruber is examined and the evidence points to Darryl Robin Kuehl, who was later convicted of the crime.

A woman is shot to death on a Florida beach. Her husband is also shot, but survives. He claims it was a robbery gone wrong, but investigators look further and learn that he had recently downloaded a song containing violent lyrics.

A small town in Colorado is on edge after a series of deadly bombings, and police race to find the culprit before he strikes again. Ultimately, it was the tools the bomber used which led investigators to the perpetrator.

Scientists analyze the memory of a murdered man's pacemaker to catch his killers.

Two women murdered in the same state park. Indiana police feared it was the work of a serial killer until the forensic evidence pointed them in two different directions.

For twelve years, the murder of a young woman went unsolved, but with the passage of time came the development of technology. Would a used tissue found at the crime scene give police the evidence they needed to bring a killer to justice?