Jane Pauley previews what viewers can expect on her new talk show, and discusses her battle with bipolar disorder.

Relationships between sisters are explored, with the main guest being Jane Pauley's sister Ann.

The value of hypnosis in losing weight, quitting smoking and reducing stress is examined.

Home decorating makeovers are featured.

Michael Gurian, author of What Could He Be Thinking?, discusses the neurological and psychological differences between men and women, and counsels various couples regarding challenges in their marriages.