Description: How can someone love you yesterday and not today? Shortly after her boyfriend sends his 12-year-old brother to break the news that she's dumped, Frankie Browne (Maeve Dermody) discovers she has a loser in love gene. Every man she goes out with will inevitably break up with her. With a lifetime of romantic failure, Frankie turns to the only genetics expert she knows: her former nemesis, a young science prodigy. Wilbur develops a maverick theory to reverse her romantic fortunes that sets into motion an unexpected and comic journey into Frankie's past of questionable romantic choices.