How a man, who spent 47 years behind bars for a crime he did not commit, turns his pain into a source for inspiration; premiere surprise guests;

Actress Tracee Ellis Ross (Black-ish (2014)); a conversion therapy leader comes out as gay;

The 18th anniversary of the 9/11 terrorism attacks; a grandmother gives birth to her son's daughter; the latest headline-making crime and legal stories;

Fashion designer Christian Siriano; surprise DNA siblings who had the same donor sperm; behind the scenes of Tamron's guest appearances on General Hospital (1963);

Actress Susan Lucci (It Takes a Lunatic (2019)); Inside Influencers: Jennifer Powell and Danielle Bernstein;

Young career women step off the corporate ladder and onto a divine new path by joining the sisterhood;

The rise of revenge porn; how victims are fighting back;

Former anchorwoman and author Gretchen Carlson discusses her latest documentaries on NXIVM and the college admissions scandal; the "Legends Series" continues with Mary Wilson of The Supremes;

Actress Catherine Oxenberg and her crusade to save her daughter from NXIVM; actors Mark-Paul Gosselaar and Tika Sumpter (Mixed-ish (2019)); interracial relationships;

American women say they were forced into underage marriage by their own families and robbed of their childhoods; an Emmy Awards recap;

The husband of a woman, whose seizures steal her memories, chronicles their life in photos and video to remind her of what they have together;

April Balascio, daughter of serial killer Edward Wayne Edwards, and her podcast co-host, Joshua Dean;

WWE Superstar Titus O'Neil and his mom discuss his turbulent childhood and story of survival, healing and transformation; two children find out they are being adopted;

Charlamagne Tha God on his journey to becoming co-host of the nationally syndicated radio show, "The Breakfast Club"; the stigma, shame and denial men face when dealing with mental illness;

The battle between anti-vaxxers and the medical community does not seem to be letting up;

Grammy Award-winning singer Erica Campbell (Mary Mary) discusses marriage, love after infidelity, and celebrating one's true beauty;

Tamron's two nephews speak out for the first time on television about their journey since their mom -- Tamron's sister -- was murdered; they shine a light on domestic violence, during domestic violence awareness month;

Whole30 co-founder Melissa Hartwig Urban discusses her past drug addiction; nurse Liz Smith, who adopted an abandoned, drug-addicted baby, with no visitors for the first five months of her life;

Fashion Friday;

Raising successful children; author Esther Wojcicki (book, "How to Raise Successful People"); Wanda Durant, mother of basketball star Kevin Durant;

Matthew Knowles discusses his breast-cancer diagnosis and whether Destiny's Child will ever reunite; "weed moms";

Ghosting: when friends suddenly cut off communications without explanation; poet and activist Yung Pueblo gives a "Tam Talk";

Fashion Friday;

Hip-hop star Rick Ross on his tell-all book and how he beat a secret addiction to drugs; Dr. Jess, Instagram therapist;

TV host Mike Rowe; former CIA covert operative Amaryllis Fox on her controversial new book about coming of age in the CIA;

Cyntoia Brown shares her story of redemption, after being sentenced to life in prison for a murder she committed at the age of 16; prosecutor Preston Shipp, who quit his job after learning he helped keep Brown behind bars;

Singer/actress Jordin Sparks on motherhood and her return to Broadway; two moms who gave birth to their daughters, after having groundbreaking uterine transplants;

Inside the opioid epidemic in America;

Actress Wendi McLendon-Covey (ABC's "The Goldbergs"); how to prepare for a divorce;

Filmmaker Tyler Perry; actress Jana Kramer and Mike Caussin discuss how their marriage survived sex addiction and infidelity;

Sports personality Skip Bayless and his wife, Ernestine Scalfani Bayless, discuss her new book; former inmates who have become successful businessmen; Jim Pitzen, whose 6-year-old son vanished in 2011;

Megan Phelps-Roper discusses her journey from hate to hope, after leaving Westboro Baptist Church; the epidemic of police suicide;

Allyson Felix, the 2012 Olympic champion who recently beat Usain Bolt's world record for the most gold medals at the track and field World Championships; Tamron's looks of the week;

Capt. Tammie Jo Shults safely lands a flight, after a mid-air explosion; Dana Bledsoe discusses healing her cancer holistically;

Rapper T.I.; writer Dan Piepenbring discusses collaborating with Prince on his memoir, "The Beautiful Ones";

An interview with Debra Newell, whose relationship inspired the blockbuster podcast, "Dirty John"; avoiding online fraud while finding love;

Tamron's first Halloween Legends Ball, with Chaka Khan;

Dan Gasby discusses his decision to start dating, while still caring for his wife, B. Smith, who has Alzheimer's; his partner Alex Lerner and daughter Dana; kitchen tricks with Lauren Braun Costello;

Undiscovered fashion designers dress Tamron all week; Sunny Hostin ("The Truth About Murder with Sunny Hostin");

A courageous woman escapes from a notorious serial killer and saves countless others; the serial killer's ex-wife; Tamron continues to highlight undiscovered fashion designers, as they dress her;

Why so many police officers are taking their own lives; personal stories of survival and what is being done to combat the crisis; Tamron continues to highlight undiscovered fashion designers, as they dress her;

Astrology: believers, deniers, and those who will not make a move, if the stars do not align; Tamron continues to highlight undiscovered fashion designers, as they dress her;

Fashion designer Andre Leon Talley; author Eve Rodsky ("Fair Play") discusses her solution to unequal labor at home; Tamron wraps up her new fashion week with another undiscovered fashion talent;

Nancy Grace tells how her life has changed, three years after leaving her popular cable news show; couples who have fallen in love after lockup;

A young woman whose church lured her into sex trafficking and how she was empowered to fight back; a woman goes undercover to revolutionize the battle against sex trafficking cases worldwide; self-dating;

Comic D.L. Hughley tells his secret to a long and successful marriage; actor Wilmer Valderrama (That '70s Show (1998) and NCIS (2003)); a couple's UberPool turns into love at first ride;

Cynthia Bailey ("The Real Housewives of Atlanta") and her fiancé Mike Hill talk about finding love in one's 50s; a woman whose doorman became her wingman, and how their story inspired a modern love movement;

Whoopi Goldberg; talk show hostess Sally Jessy Raphael; some of the most unforgettable and favorite actors, musicians, and entertainers of the past few decades;

Award-winning director/producer Ava DuVernay; relationship expert/author Shan Boodram tells how to be a better partner; Montell Jordan performs;

Grammy award-winning producer, songwriter, and composer David Foster performs; another mystery guest;

Comic Gary Gulman (Gary Gulman: The Great Depresh (2019) and Joker (2019)) tells how being funny helped him find joy again; a popular sitcom star is the mystery guest;

Model and actress Lauren Hutton tells her secrets to looking great at any age and discusses her pioneering career; a favorite sitcom star is the mystery guest;

Singer, actress, author, entrepreneur, and living legend Patti LaBelle; actress/singer Deborah Cox (Influence (2020));

Former NFL All-Pro and "America's Got Talent" finalist Jon Dorenbos tells how magic saved his life;

Tamron gives thanks with former Destiny's Child singer Kelly Rowland; Julia Collin Davison ("America's Test Kitchen"), with the help of child chefs, prepares traditional and non-traditional, child-approved Thanksgiving dessert recipes;

Polyamorous relationships; whether it is too personal to ask someone when they are having a baby; dressing for one's body type;

Actress Candace Cameron Bure ("Fuller House"); how interfaith couples navigate the holidays;

"Project Runway" judge and author Elaine Welteroth; teens discuss sexual fluidity;

Actress Jane Lynch ("The Marvelous Mrs. Maisel" and "A Swinging Little Christmas Tour"): homicide detective Fil Waters ("The Interrogator");

Forgiving the unforgivable: a moving conversation with the mother of a killer and the mother of his victim;

Dr. Ruth Westheimer; Dionne Warwick performs;

A special holiday show; a single father tells how adopting five siblings, under the age of 5, changed his life; holiday gifts for everyone on one's list; Tamron's holiday surprises;

Three "Marvel's Hero Project" children are real-life superheroes; a man, who was left in a dumpster as a baby, now owns a multi-million-dollar telecommunications company;

Miss Universe Zozibini Tunzi, Miss USA Chelsie Kryst, and Miss Teen USA Kaliegh Garris talk about being the first women of color to hold three major pageant titles at the same time; Ring CEO Jamie Siminoff shares his success story;

LaChanze ("A Christmas Carol") and her daughter, Celia Rose Gooding ("Jagged Little Pill"), perform; three siblings, who survived a neglected childhood with a mom addicted to drugs and alcohol, are now thriving;

Actress Holly Robinson Peete (A Family Christmas Gift (2019)); the cast of Tony Award winner "Dear Evan Hansen (2021)" perform their iconic song; chef Jacques Torres (Netflix's Nailed It! (2018)) whips up a holiday dessert;

Former NFL player Jeff Rohrer and his ex-wife Heather; Dr. Drew Pinsky takes questions from the audience, and discusses his crusade to clean up inner cities;

Inspirational stories of weight-loss; how to get healthier in 2020; clearing the clutter; clearing the mind with popular organization expert Peter Walsh;

Whether new, meatless fast-food menu options are healthy; exercise physiologist Marco Borges shows a simple switch to losing weight; inspirational fit-over-50 success stories; fitness guru Jorge Cruise;

Motivational speaker Gabrielle Bernstein talks about tuning in to one's intentions and self-care for the new year; revealing a story of revenge and regret;

"Property Brothers" Drew and Jonathan Scott discuss making a house a home; the potential dangers of the detox obsession;

Yara Shahidi ("grown-ish"); 11-year-old Skye Turner portrays Tina Turner on Broadway and Aretha Franklin on the big screen;

Kandi Burruss (The Real Housewives of Atlanta (2008)); Jennifer Hyman and Blaire Walsh, Rent the Runway, a fashion show solving everyday women's fashion dilemmas;

Actors Tyler Perry, Phylicia Rashad, Cicely Tyson, Crystal Fox, and Bresha Webb ("Tyler Perry's A Fall From Grace");

Martin Luther King Day; fit-over-50 stories; Tamron's favorite workout; a couple who transformed their bodies and lives, together;

Nev Schulman and Kamie Crawford (MTV's Catfish: The TV Show (2012));

Apyrl Michelle Brown (Netflix's "Botched Up Bodies") discusses receiving a black-market silicone injection and nearly dying;

Why women are not getting enough sleep; ways to fall asleep and stay asleep;

Supermodel-turned-super-mogul Kathy Ireland with a surprising new venture; comic/author Tommy Davidson (memoir, "Living in Color");

Emmy, Grammy, and Tony Award winner and cultural phenomenon Billy Porter; embracing one's personal style; the Royal House of LaBeija performs;

Up-and-coming designers dress Tamron from head to toe; supermodel and fashion icon Beverly Johnson;

Members of Netflix's "Cheer" squad; a talented new designer's fashions;

Actress Tia Mowry (Family Reunion (2019)); a new designer's fashions;

Family or Fiancé (2019) host Tracy McMillan and couple Chris and Falasha; the work of another new designer;

Fashion legend Andre Leon Talley; Star Jones, with the message she is spreading 10 years after her open-heart surgery;

Behind the scenes with the stars and fashion at the Oscars;

Love and relationship series kicks off with Nick and Vanessa Lachey ("Love Is Blind"); a woman who will only date a man who is in therapy and committed to his own emotional health and growth;

Grammy-winning rapper Timbaland on transforming the music industry to transforming himself with diet and fitness, after battling a painkiller addiction;

Actress and activist Fran Drescher (Indebted (2020)); actress Ambyr Childers (You (2018)); Caroline Kepnes, the author of the books, focused on obsessive love, that inspired the series, You (2018));

Author and inspirational speaker DeVon Franklin reveals what women and men need to know for a better relationship; Valentine's Day gifts;

A teenager has a seizure and is saved by someone 5,000 miles away: an emotional meeting between them; an inspirational talk with Bishop T.D. Jakes;

The real-life inspiration for the new ABC series, "For Life"; the effect of celebrities pushing for criminal justice reform;

Michelle Knight, held in captivity for more than 10 years; Elizabeth Smart, held in captivity for nine months, when she was 14;

Couples' love stories start with tweets and spark the hashtag #WeMetOnTwitter;

Ways to cope with, accept, and embrace grief; secrets to living a happy and fulfilled life, after tragedy;

Talk show legends Ricki Lake, Montel Williams, and Rolonda Watts;

Successful female entrepreneurs; how to be a "lady boss";

Actor and director Blair Underwood; a teacher's life changes, for the better, after adopting a child in need of a kidney transplant;

A raw and real conversation with transgender kids about what they face in society today; raising transgender kids; sports and transgender athletes;

Author Edie Falco ("Tommy"); author Glennon Doyle (book, "Untamed"); Angelique Kidjo performs;

Dan Abrams, Tom Morris Jr., and Sgt. Sean Larkin (Live PD (2016)); Jan Broberg (Netflix documentary, Abducted in Plain Sight (2017)), kidnapped twice as a teenager;

A show dedicated to pets; animals who earn thousands of dollars per social media post; dog trainer Travis Brorsen (My Big Fat Pet Makeover (2017)); when pets become life-saving heroes;

The latest news and information on the coronavirus; the truth about marriage, with Cat and Nat; podcasters Adam and Danielle Silverstein; high school classmates who fell in love 46 years after graduation;

Actress Angela Bassett ("9-1-1"); cast members from Broadway's "Frozen", "The Lion King", and "Aladdin", and a special performance from "Aladdin";

Venus Williams tells how she is encouraging people to stay healthy and active, while self-quarantining; love in the time of quarantine; revisiting a conversation with supermodel and fashion icon Beverly Johnson;

Chris Harrison ("The Bachelor"); Colton Underwood ("The First Time: Finding Myself and Looking for Love on Reality-TV"); New York Times columnist Charles M. Blow discusses COVID-19;

Prison inmates, their families, and those working within the system respond to the potential release of select prisoners to prevent the spread of the Coronavirus.

Andrew Yang, former 2020 Democratic presidential candidate; financial expert Suze Orman (book, "The Ultimate Retirement Guide for 50+" and podcast "Women and Money").

Kelly Ripa and Ryan Seacrest (Live with Kelly and Mark (1988)); Olivia Munn (Netflix's Love Wedding Repeat (2020)); couples from TLC's "90 Day Fiance" talk about the new spin-off, "90 Day Fiance: Self Quarantine";

Actors Nathalie Kelley and Victor Rasuk (The Baker and the Beauty (2020)); overindulging in food and alcohol during the pandemic quarantine; an ER doctor loses temporary custody of her 4-year-old daughter to her ex-husband, over Coronavirus fears;

Deepak Chopra advises on well being during the pandemic; Dr. Anita Phillips discusses dealing with loneliness, isolation, and loss; a funeral director tells how the death toll is overwhelming last responders and how people are mourning;

Tamron celebrates Moses' first birthday; Dennis Quaid (podcast "The Dennissance"); celebrity pastry chef and chocolatier Jacques Torres ("Nailed It"); Holly Robinson Peete discusses The HollyRod Foundation;

Atlanta Mayor Keisha Lance Bottoms; Tamron explores the reality of poverty and hunger during the COVID-19 pandemic; Rev. William Barber II; baseball legend Cal Ripken Jr.

Actress Pamela Adlon (Better Things (2016)); advice on dealing with the emotional toll COVID-19 is taking on teens; one young woman's dream of Olympic gold is now on hold.

Singer JoJo discusses her upcoming album; the fashion industry and celebrity designers use their talents to make a difference during the Coronavirus crisis;

Actress Tiki Sumpter ("Mixed-ish" and "The Haves and the Have Nots"); actor Peter Gallagher ("Zoey's Extraordinary Playlist" and "Grace and Frankie"); tips on taking care of hair, skin, nails, and more from home;

Lecy Goranson ("The Connors"); Cedric Yarbrough ("Reno 911"); the challenges of having children via surrogacy, adoption, and fertility treatments during the pandemic;

How people in other countries are getting through the global pandemic, and how their experiences can help viewers in the U.S.; an update from a family living in Wuhan, China.

Tamron celebrates moms who are going the extra mile, doing incredible things, outside of their normal work and everyday lives, to support people on the front lines while in quarantine;

Nurses, medical workers, and advocates risk their own health to care for patients with COVID-19;

Philantropist Melinda Gates; domestic violence in quarantine; a mother and her four children flee an abusive relationship, as the Coronavirus pandemic hits the U.S.; a nurse survives COVID-19 but loses her life to domestic violence;

The Coronavirus disrupts college decisions and life for students nationwide; Kevin O'Leary ("Shark Tank"); Alfonso Ribeiro ("America's Funniest Home Videos") bring cute, crazy, comical videos people are sharing during quarantine;

Dylan McDermott (Netflix's "Hollywood"); businesses that are reopening; in Flint, Michigan, there is still a clean water crisis, in addition to COVID-19; a doctor on a mission to tackle COVID-19 misinformation;

Style icon Andre Leon Talley discusses his revealing new memoir; pets help people get through the quarantine; Drs. Ben and Erin Schroeder (Nat Geo Wild's Heartland Docs, DVM (2020));

Anthony Anderson ("black-ish"); chef Art Smith digs into his Southern roots with an easy recipe to cook at home for Memorial Day; singer/songwriter Tamar Braxton and her longtime hairstyle, Johnny Wright ("To Catch a Beautician");

Erin and Ben Napier (HGTV's Home Town (2016)); Iyanla Vanzant (OWN's Fear Not with Iyanla Vanzant (2020)); Michelle Herd discusses moving forward, after the murder of her 7-year-old daughter; a neighbor's quick thinking helps save a life;

Singer John Legend (album, "Bigger Love"); actresses Lynn Whitfield and Merle Dandridge (OWN's Greenleaf (2016)); making the best of travel in uncertain times;

From creative parenting and beauty hacks to fashion fixes and sleep solutions, there is a hack for just about everything; simple and inexpensive design hacks; how to spend less time in the kitchen;