With a big cartel shipment of heroin about to arrive in Laredo, the LPD team conducts a citywide crackdown of suspected heroin dealers to squeeze information out of them about where and when the drugs will arrive.

Sifuentes and Roly are determined to take down Quack, one of Laredo's most notorious heroin dealers. But it won't be easy--Quack has ducked the LPD's attempts to stop him twice before.

The team's K-9 sniffs out a package containing black tar heroin hidden in a child's teddy bear. Linking the parcel with a residence called the "Spiderhouse," the LPD hopes it will lead them to the distributor of the deadly form of heroin.

Through information from a trusted C.I., LPD Narcotics busts a stash house holding cocaine and guns, plus a ledger filled with information that could help them put a heavy cocaine operation out of business.

After the murder of an ICE agent in Mexico, Sifuentes is determined to hit the cartels where it hurts, and a local casino's connection to a prostitution ring may give him the chance he needs.