Marc is happy things are going well in his professional and personal life but becomes his own worst enemy as he sabotages a guest spot on Talking Dead (2011) and ruins a relationship.

Marc is annoyed that none of his old pals can hang anymore on a regular basis. Although after bonding with Ray Romano, Marc pursues a friendship, ignoring Kyle's warnings that Romano is on a different level.

With their relationship stagnating, and reaching a critical crossroads, Marc and Jen enter couples therapy, but the advice they get from two married professionals causes even more problems.

Marc's mom comes to visit. He wants to avoid her and pawns her off on a friend's Dad. The plan backfires when the older couple hit it off too well and Marc has to parent his Mom through an STD scare.

Marc explores a friend with benefits relationship with Caroline Rhea, while dealing with an unwanted present from Dave Anthony. Both give him material to reflect on emotional attachment.

Marc is dreading an upcoming road trip. He's tired of doing the same old material and is anxious at the thought of writing new stuff but his anxiety reaches a peak when he discovers a sore that he believes to be mouth cancer.

Marc hits it off with Rachael Harris by comparing their bad relationship scars. When Marc pursues her, she wants him to prove he's over his anger issues by joining her yoga class.

As Marc weighs a lucrative offer from a huge corporate media entity, he discovers, and tries to help, a lone, unique, old-school radio DJ, still doing his show the old-fashioned way.

Trying to lead a simpler life, Marc immerses himself in his vinyl-collecting hobby but a chance encounter with a woman he meets in the record store parking lot snowballs into just the kind of chaos he's been trying to avoid.

When Marc accidentally steals a joke from another comedian, he feels guilty. That guilt is put to the test when the comic insists Marc help his career in return.

Feeling guilty over his recent success, Marc takes a road trip with Andy and Dave to help a troubled buddy, but everybody's friendship gets tested once things take a bizarre turn.