A man is impaled in the mouth by a section of pipe after he runs through a chain link fence; A newlywed starts bleeding heavily inexplicably; Two prisoners are brought in. Are they lying or telling the truth.

Doctors suspect an apparent child abuse victim might actually have a medical condition causing the injuries; A white German shepherd shows up in the ER on Halloween; A neurologist happens upon a motorcycle rider who has just wrecked.

A shooting victim's Rottweiler gets loose in the ER; A woman with a five-month-old baby is suffering from heart failure; A comatose man comes into the ER with a suspicious rash.

A doctor struggles with the decision to revive an older patient after prolonged CPR. Two nurses encounter a stabbing victim on the street and try to save him. A doctor on a cruise ship finds that her dream job has become a nightmare.