Daimon Helstrom investigates a possessed young boy. In San Francisco, Ana Helstrom stages an auction to expose a criminal. Disturbing events at St. Teresa's cause concern as the siblings' estranged Mother remains hospitalized.

A horrific accident leads Daimon and Gabriella fighting to save a man's soul, while a dark force attempts to stop them.

Daimon and Ana learn more about the destruction their father left in his wake. With Gabriella, they pay a visit to a potential victim and find themselves in deeper than they ever could have imagined.

A demonic enemy brings together an unusual group. Daimon and Ana travel to San Francisco in search of Yen and an artifact that may help defeat the enemy.

Things are not what they seem as Mother's health sharply declines. As Ana searches for Yen, Gabriella offers counsel to a student struggling to understand how demons live among us.

A dark force creates a melee forcing Hastings and Ana to work together. Daimon and Gabriella discover the events of the Blood Hotel are connected. The demon's identity is revealed, shaking Ana and Daimon to their core.

With a powerful demon looking for a new host and Ana struggling to control her darker urges, Daimon is offered a proposition from The Blood.

Relationships deepen as stakes increase. To save a life, Hastings and Ana must do the unthinkable. Gabriella and Daimon journey to his childhood home in search of an old relic. A mother loses a son but gains an heir.

Daimon and Gabriella find themselves in disturbing new territory. Ana has to make a decision that will change the course of the siblings' lives in irreversible ways. Victoria tries to make amends but she may be too late.

Ana and Daimon fight to save a soul but only Yen can be victorious. Gabriella's newfound perspective challenges Daimon's beliefs, creating rifts among the group. Victoria unites with Daimon and Ana, but their victory comes at a cost.